Vitiligo is a long term skin condition characterized by patches of the skin losing their pigment. The research has found that the onset vitiligo is close related to the disorder of endocrine system. In this article I will elaborate what’s mean is the endocrine autoimmune disorder, and some clinical data about the vitiligo with the endocrine system disorder.
The endocrine system co-ordinates the body’s physiology and assists in responses to internal or external stimuli. Endocrine cells produce hormones that are secreted into the bloodstream, and act at distant sites throughout the body.
The endocrine autoimmune disorders are similar to those for all autoimmunity. The disorders develop gradually, and may take several years to show clinically recognizable symptoms. Autoimmunity seems to arise from multiple factors that includes a genetic predisposition combined with specific triggers. The diagnosis of endocrine autoimmunity by a physician involves assessing symptoms and measurement of a relevant hormone to determine if it is within normal levels. Antibody tests to specific cellular components often are performed to confirm autoimmunity. Treatment for endocrine autoimmunity usually consists of hormone replacement or agents to suppress overactive glands.
The relevant statistics indicates the endocrine have a close relationship with the vitiligo. The specialist analyzes 1020 cases with the vitiligo.
There are 75 of 160 cases age from 12 to 20 years suffer from the vitiligo at the menarche period. There are 293 cases during a child-bearing period, 8 cases occur vitiligo during the gestation period, five cases after prenatal period, lactation.
There are 35 cases from 44 to 45, 16 cases occur vitiligo at the same time the menopause.
The above statistics have fully indicated that the onset of vitiligo is close related with the endocrine system of body, others research and experiment also indicated that many endocrine hormones have a significant effect to the metabolism of the melanin, such as Adrenocorticotropic hormone, Melanin cell stimulant, corticosteroids, melatonin.