The doctors’ answer is certain. There are many diseases that can accompany with the onset of vitiligo, such as psoriasis, alopecia areata, dermatographism, lichen sclerosis et atrophicus, twenty-nail dystrophy, erythema dyschromicum perstans, follicular atrophoderma, and basal cell carcinoma.
Psoriasis is a common skin disease in clinic. The typical characteristic is a kind of chronic relapsing erythema scales sex skin disease. The causes are concerned with inheritance, immunity, endocrine, infection, and spirit factors. Clinical researches indicate that psoriasis patients have increased observably compared to normal people. At the same time, many psoriasis patients’ lesion positions don’t have vitiligo skin lesion. But some psoriasis patients’ lesion will get depigmentation. And pigment loss spots usually occur between psoriasis lesion and normal skin. This may be because that psoriasis patients’ melanophore are vulnerable to damage.
Alopecia areata is a common local hair loss disease in clinic. The cause is related to spirit tension, endocrine disorder and autoimmunity. There are reports indicating that the rate of vitiligo coexistence with alopecia areata is four times as pure vitiligo patients. That may be because neuropsychical factor will generate influence to melanophore by immunity system.
Dermatographism is also called factitious urticaria. Normally, there will be skin itch or scorching hot first. The causes are relevant to spirit factor, immunity reaction and allergic reaction.
Lichen sclerosis et atrophicus and white-spot disease. The typical lesion appearance is porcelain flat papule. The surface has small comedones hair follicle keratin plug. The surrounding is blush. Later there will be skin and focus sclerosis and atrophy, accompanied with depigmentation spots. The disease usually occurs on genitals, both man and woman. It is related to inheritance, sex hormone level and autoimmunity and etc. If vitiligo coexists with lichen sclerosis, it may be because during the melanin synthesis produce, the metabolism and other factors affect. These two diseases are related to immunity pathological mechanism.